20 Steps to Better Wireframing
19) Choose the Right Tools
Pen and paper is often the way to start. It is much easier and faster than using a computer and lets you get thoughts and ideas down as the concept evolves.
Once you start creating the document our advice would be to use the tool you’re most comfortable with. Developers for example may use Microsoft Visio, project managers PowerPoint, Designers Adobe Fireworks.
I think that the wireframe should be a document though rather than something interactive (like design, it can be a distraction) and therefore creating HTML may not be the best thing.
There are a number of specific tools for wireframing, for example Balsamiq provides an environment for quickly adding and customising common interface elements. They have given it a hand drawn feel to provide a visual lift while not actually being design.
(Link: 20 Steps to Better Wireframing)
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